Executive Director, US Launch Lead Prostate (STEAP-1 bi-specific)

Company: Amgen
Location: Thousand Oaks
Posted on: January 3, 2026

Job Description:

At Amgen, if you feel like you are a part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. What you will do Lets do this. Lets change the world. In this vital role the Executive Director, US Launch Lead for prostate cancer (STEAP-1 bi-specific) is accountable for designing and delivering the US launch strategy for one of Amgens most strategically important oncology products. This role owns the end-to-end US commercial launchfrom early market shaping through post-launch executionand serves as the single-point commercial leader responsible for ensuring launch excellence, durable uptake, and long-term sustainable brand growth.This product represents a significant opportunity to advance Amgens oncology portfolio and redefine treatment paradigms. Success in this role requires a seasoned commercial leader with deep experience in launch planning, marketing excellence, market creation, and cross-functional orchestrationsomeone who can translate scientific innovation into a compelling, differentiated brand narrative that resonates with customers and drives adoption at scale.The Executive Director is a member of the Oncology Business Unit Senior Leadership Team (OBU SLT) and plays a critical role in shaping the broader US Oncology commercial strategy, culture, and operating model. Key responsibilities include: US Launch Strategy & Readiness Working closely with core partners such as Global Commercial team to lead the comprehensive US launch strategy, ensuring seamless execution from pre-approval through launch and into early commercialization Define the launch ambition, success metrics, and critical path milestones across all functions Lead scenario planning and launch risk mitigation across regulatory outcomes, competitive dynamics, access scenarios, and supply considerations. Collaborate on launch strategy and readiness with key functions including Field, Access, Medical, Patient Support, Digital, and Corporate Affairs Market Definition & Market Creation Define the US market opportunity, including target patient populations, lines of therapy, care pathways, and key decision-makers Identify unmet needs, adoption barriers, and behavioral drivers; translate these insights into market-shaping strategies Serve as the in-house US commercial authority on product, market, competitive landscape, and evolving standard of care Brand Strategy, Positioning & Messaging Leverage Global strategic platform to create the US brand strategy, value proposition, and long-term growth narrative Lead development of the core messaging platform, ensuring scientific credibility, customer relevance, and strategic differentiation. Ensure consistent, compelling storytelling across all touchpointsHCP, payer, patient, and internal audiences Cross-Functional & Matrix Leadership Lead a highly integrated, cross-functional launch team spanning Marketing, Global Commercial, Sales, Medical, Market Access, HEOR, Regulatory, Legal, Digital, and Operations Establish clear governance, decision rights, and accountability across the matrix. Partner with Global teams to ensure strong US input into global strategy, while tailoring execution to US market realities Field & Access Enablement Ensure the Field organization is launch-ready with clear strategy, compelling materials, and confidence in the value story Partner with Market Access to shape pricing, reimbursement, and contracting strategies aligned with brand objectives and customer needs Oversee development of patient support and access solutions that enable rapid and equitable uptake People, Culture & Leadership Build, develop, and inspire high-performing commercial team, modeling leadership behaviors that promote accountability, inclusion, and continuous improvement Act as a visible, decisive leader who brings clarity amid ambiguity and momentum through complexity Partner with the BU General Manager, OBU SLT, and other Brand Leads to reinforce a strong sense of purpose, collaboration, and executional excellence across the OBU What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree & 6 years of Marketing experience OR Masters degree & 10 years of Marketing experience OR Bachelors degree & 12 years of Marketing experience AND 6 years of managerial experience directly managing people and/or leading teams, projects, programs, or resource allocation. Preferred Qualifications: 8 years of progressive commercial leadership experience within the biopharmaceutical or biotechnology industry Leading one or more major US product launches, ideally in oncology (particularly prostate cancer) or other complex specialty markets Experience launching first-in-class, best-in-class, or market-creating assets strongly preferred Ability to translate complex science and data into clear, differentiated commercial strategies Deep understanding of US market access, pricing, reimbursement, and policy dynamics Analytical mindset with experience using insights, forecasting, and scenario planning to guide decisions Experience leading large, cross-functional teams in a highly matrixed environment Executive presence with the ability to distill a strong brand narrative, influence senior leaders, challenge constructively, and drive alignment Experienced people leader with a passion for developing talent and building high-performing teams Oncology experience strongly preferred, with additional preference for experience in prostate cancer; experience with immuno-oncology, novel mechanisms, or biomarker-driven therapies is a plus What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The annual base salary range for this opportunity in the U.S. is 286,327 to 350,886.00. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans and bi-annual company-wide shutdowns Flexible work models, including remote work arrangements, where possible As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.Sponsorship for this role is not guaranteed.

Keywords: Amgen, Lancaster , Executive Director, US Launch Lead Prostate (STEAP-1 bi-specific), PR / Public Relations , Thousand Oaks, California